Publications: Australian Animal Experimentation

@article{nokey,

title = {Anti-Drug antibodies in pigtailed macaques receiving HIV broadly neutralising antibody PGT121},

author = {Wen Shi Lee, Arnold Reynaldi, Thakshila Amarasena, Miles P. Davenport, Matthew S. Parsons and Stephen J. Kent},

doi = {10.3389/fimmu.2021.749891},

year  = {2021},

date = {2021-11-21},

urldate = {2021-11-21},

journal = {Frontiers in Immunology},

volume = {12},

note = {University of Melbourne},

keywords = {Macaque},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Coformulation with Tattoo Ink for Immunological Assessment of Vaccine Immunogenicity in the Draining Lymph Node},

author = {Isaac M. Barber-Axthelm, Hannah G. Kelly, Robyn Esterbauer, Kathleen M. Wragg,

Anne M. Gibbon, Wen Shi Lee, Adam K. Wheatley, Stephen J. Kent, Hyon-Xhi Tan,

and Jennifer A. Juno

C},

doi = { https://doi.org/10.4049/jimmunol.2001299},

year  = {2021},

date = {2021-07-15},

urldate = {2021-07-15},

journal = {The Journal of Immunology},

volume = {207},

issue = {2},

pages = {735-744},

abstract = {Characterization of germinal center B and T cell responses yields critical insights into vaccine immunogenicity. Nonhuman primates are a key preclinical animal model for human vaccine development, allowing both lymph node (LN) and circulating immune responses to be longitudinally sampled for correlates of vaccine efficacy. However, patterns of vaccine Ag drainage via the lymphatics after i.m. immunization can be stochastic, driving uneven deposition between lymphoid sites and between individual LN within larger clusters. To improve the accurate isolation of Ag-exposed LN during biopsies and necropsies, we developed and validated a method for coformulating candidate vaccines with tattoo ink in both mice and pigtail macaques. This method allowed for direct visual identification of vaccine-draining LN and evaluation of relevant Ag-specific B and T cell responses by flow cytometry. This approach is a significant advancement in improving the assessment of vaccine-induced immunity in highly relevant nonhuman primate models.},

note = {Macaques - Monash Animal Research Platform Gippsland Field Station; Mice University of Melbourne},

keywords = {Macaque, Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Topographic organization of the ‘Third-Tier’ dorsomedial visual cortex in the macaque},

author = {Hadjidimitrakis K, Bakola S, Chaplin TA, Yu HH, Alanazi O, Chan JM, Worthy KH, Rosa MGP.},

url = {https://www.jneurosci.org/content/39/27/5311},

year  = {2019},

date = {2019-07-03},

note = {Monash University},

keywords = {Macaque, Non-human primates},

pubstate = {published},

tppubtype = {article}

}