Publications: Australian Animal Experimentation

@article{nokey,

title = {Coformulation with Tattoo Ink for Immunological Assessment of Vaccine Immunogenicity in the Draining Lymph Node},

author = {Isaac M. Barber-Axthelm, Hannah G. Kelly, Robyn Esterbauer, Kathleen M. Wragg,

Anne M. Gibbon, Wen Shi Lee, Adam K. Wheatley, Stephen J. Kent, Hyon-Xhi Tan,

and Jennifer A. Juno

C},

doi = { https://doi.org/10.4049/jimmunol.2001299},

year  = {2021},

date = {2021-07-15},

urldate = {2021-07-15},

journal = {The Journal of Immunology},

volume = {207},

issue = {2},

pages = {735-744},

abstract = {Characterization of germinal center B and T cell responses yields critical insights into vaccine immunogenicity. Nonhuman primates are a key preclinical animal model for human vaccine development, allowing both lymph node (LN) and circulating immune responses to be longitudinally sampled for correlates of vaccine efficacy. However, patterns of vaccine Ag drainage via the lymphatics after i.m. immunization can be stochastic, driving uneven deposition between lymphoid sites and between individual LN within larger clusters. To improve the accurate isolation of Ag-exposed LN during biopsies and necropsies, we developed and validated a method for coformulating candidate vaccines with tattoo ink in both mice and pigtail macaques. This method allowed for direct visual identification of vaccine-draining LN and evaluation of relevant Ag-specific B and T cell responses by flow cytometry. This approach is a significant advancement in improving the assessment of vaccine-induced immunity in highly relevant nonhuman primate models.},

note = {Macaques - Monash Animal Research Platform Gippsland Field Station; Mice University of Melbourne},

keywords = {Macaque, Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Melatonin augments the neuroprotective effects of hypothermia in lambs following perinatal asphyxia},

author = {Aridas, et al },

url = {https://pubmed.ncbi.nlm.nih.gov/34032315/},

year  = {2021},

date = {2021-06-20},

note = {Monash University, Hudson Institute of Medical Research},

keywords = {Sheep},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Lévy walk dynamics explain gamma burst patterns in primate cerebral cortex  },

author = {Liu Y, Long x, Martin PR, Solomon SG, Gong P.},

url = {https://pubmed.ncbi.nlm.nih.gov/34131276/},

year  = {2021},

date = {2021-06-15},

note = {University of Sydney},

keywords = {Non-human primates},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {The efficacy of a nanosynthetic bone graft substitute as a bone graft extender in rabbit posterolateral fusion},

author = {Jordan C. Conway, Rema A. Oliver, Tian Wang, Daniel J. Wills, Joe Herbert, Tom Buckland, William R. Walsh, Iain R. Gibson},

doi = {10.1016/j.spinee.2021.05.017},

year  = {2021},

date = {2021-05-19},

urldate = {2021-05-19},

volume = {21},

pages = {1925-1937},

publisher = {The Spine Journal},

note = {University of New South Wales},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {NK1 antagonists attenuate tau phosphorylation after blast and repeated concussive injury},

author = {Corrigan F, Cernak I, McAteer K, Hellewell SC, Rosenfeld JV, Turner RJ, & Fink R},

url = {https://www.nature.com/articles/s41598-021-88237-0},

year  = {2021},

date = {2021-04-23},

note = {University of Adelaide},

keywords = {Rats},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Neurochemical changes in the primate lateral geniculate nucleus following lesions of striate cortex in infancy and adulthood: implications for residual vision and blindsight},

author = {Atapour N, Worthy KM, Rosa MG.},

url = {https://link.springer.com/article/10.1007/s00429-021-02257-0},

year  = {2021},

date = {2021-03-20},

urldate = {2021-03-20},

note = {Monash University},

keywords = {Marmosets, Non-human primates},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = { Postpartum ovulation and early pregnancy in the menstruating spiny mouse},

author = {McKenna, J. Bellofiore B., Dimitriadis E., Temple-Smith , P.},

url = {https://www.nature.com/articles/s41598-021-84361-z},

year  = {2021},

date = {2021-03-05},

note = {Monash University},

keywords = {Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Subcutaneous ω-Conotoxins Alleviate Mechanical Pain in Rodent Models of Acute Peripheral Neuropathy},

author = {Md Mahadhi Hasan, Hana Starobova, Alexander Mueller, Irina Vetter, Richard J Lewis},

doi = {10.3390/md19020106},

year  = {2021},

date = {2021-02-11},

urldate = {2021-02-11},

journal = {Marine Drugs},

abstract = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917901/

},

note = {University of Queensland},

keywords = {Mice, University of Queensland},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Single level posterolateral lumbar fusion in a New Zealand White rabbit (Oryctolagus cuniculus) model: Surgical anatomy, operative technique, autograft fusion rates, and perioperative care},

author = {James D Crowley, Rema A Oliver, Michael J Dan, Daniel J Wills, John W Rawlinson, Rebekah A Crasto, James M O'Connor, Gregory J Mitchell, Christopher J Tan, William R Walsh},

url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC7984023/?utm_source=chatgpt.com},

doi = {https://doi.org/10.1002/jsp2.1135},

year  = {2020},

date = {2020-12-23},

urldate = {2020-12-23},

journal = {JOR Spine},

volume = {4},

issue = {1},

abstract = {This study outlines a method for performing back fusion surgery on adult female New Zealand White rabbits to test new bone-growing materials for human spine treatments, focusing on the lower back (lumbar area) at the L4-L5 spot. First, vets checked the rabbits' bone maturity with X-rays and live scans of their legs; then, under anesthaesia using injections like buprenorphine for pain and midazolam for calm, plus gas (isoflurane), they got fluids, antibiotics, and heat support. For the surgery, fur was shaved from the back and hip, skin cut open and a small chunk of the rabbit's own bone (about 2 teaspoons from the hip crest) was scooped out with tools; sometimes bone marrow was sucked from the upper leg bone with a needle; next, through a back cut between back muscles, the bony side arms (transverse processes) of L4 and L5 were scraped raw with a drill to make them bleed and ready for healing, then the bone bits were packed on both sides without screws or rods to let natural fusion happen over 12 weeks. Across 868 rabbits, fusion worked in about 77% by feel and 70% by X-ray, with most rabbits having 7 lower back bones, and issues like wound opening from scratching were fixed with collars and special high-hay diets in group pens.},

note = {University of New South Wales},

keywords = {Rabbits, Spinal fusion},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Mapping the neural circuitry of predator fear in the nonhuman primate},

author = {Quentin Montardy, William C Kwan, Inaki C Mundinano, Dylan M Fox, Liping Wang, Cornelius T Gross, James A Bourne},

url = {https://pubmed.ncbi.nlm.nih.gov/33263778/},

doi = {10.1007/s00429-020-02176-6},

year  = {2020},

date = {2020-12-02},

urldate = {2020-12-02},

abstract = {In rodents, innate and learned fear of predators depends on the medial hypothalamic defensive system, a conserved brain network that lies downstream of the amygdala and promotes avoidance via projections to the periaqueductal gray. Whether this network is involved in primate fear remains unknown. To address this, we provoked flight responses to a predator (moving snake) in the marmoset monkey under laboratory conditions. We combined c-Fos immunolabeling and anterograde/retrograde tracing to map the functional connectivity of the ventromedial hypothalamus, a core node in the medial hypothalamic defensive system. Our findings demonstrate that the ventromedial hypothalamus is recruited by predator exposure in primates and that anatomical connectivity of the rodent and primate medial hypothalamic defensive system are highly conserved.},

note = {Monash University},

keywords = {Marmosets, Non-human primates},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {A Comparative Study of Engineered Dermal Templates for Skin Wound Repair in a Mouse Model. },

author = {Banakh I, Cheshire P, Rahman M, Carmichael I, Jagadeesan P, Cameron NR, Cleland H. Akbarzadeh S.},

url = {https://www.mdpi.com/1422-0067/21/12/4508},

year  = {2020},

date = {2020-06-05},

note = {Monash University, Alfred Health},

keywords = {Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Sex-specific metabolic responses to 6 hours of fasting during the active phase in young mice},

author = {Therese Freire, Alistair M. Senior, Ruth Perks, Tamara Pulpitel, Ximonie Clark, Amanda E. Brandon, Devin Wahl, Luke Hatchwell, David G. Le Couteur, Gregory J. Cooney, Mark Larance, Stephen J. Simpson, Samantha M. Solon-Biet},

url = {https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP278806},

doi = {https://doi.org/10.1113/JP278806},

year  = {2020},

date = {2020-03-21},

abstract = {There is growing interest in understanding the mechanistic significance and benefits of fasting physiology in combating obesity. Increasing the fasting phase of a normal day can promote restoration and repair mechanisms that occur during the post-absorptive period. Most studies exploring the effect of restricting food access on mitigating obesity have done so with a large bias towards the use of male mice. Here, we disentangle the roles of sex, food intake and food withdrawal in the response to a short-term daily fasting intervention, in which food was removed for 6 h in the dark/active phase of young, 8-week-old mice. We showed that the removal of food during the dark phase impaired glucose tolerance in males and females, possibly due to the circadian disruption induced by this feeding protocol. Although both sexes demonstrated similar patterns of food intake, body composition and various metabolic markers, there were clear sex differences in the magnitude and extent of these responses. While females displayed enhanced capacity for lipogenesis and triglyceride storage, they also had low fasting insulin levels and an increased potential for utilizing available energy sources such as fat for energy through β-oxidation. Our results highlight the intrinsic biological and metabolic disparities between male and female mice, emphasizing the growing need for the inclusion of both sexes in scientific research. Furthermore, our results illustrate sex-specific metabolic pathways that regulate lipogenesis, obesity and overall metabolic health.},

note = {Charles Perkins Centre, University of Sydney. },

keywords = {Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Sex specific metabolic responses to 6 hours fasting during the active phase in young mice},

author = {Therese Freire, Alistair M. Senior, Ruth Perks, Tamara Pulpitel, Ximonie Clark, Amanda E. Brandon, Devin Wahl, Luke Hatchwell, David G. Le Couteur, Gregory J. Cooney, Mark Larance, Stephen J. Simpson, Samantha M. Solon-Biet},

url = {https://pubmed.ncbi.nlm.nih.gov/32198893/},

year  = {2020},

date = {2020-03-21},

urldate = {2020-03-21},

note = {Charles Perkins Centre, University of Sydney},

keywords = {Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Human induced pluripotent stem cell-derived GABAergic interneuron transplants attenuate neuropathic pain},

author = {Manion J., Khong T., Harney D., Littleboy J.B., Ruan T., Loo L., Costigan M., Larance M., Caron L., Neely G.G.},

url = {https://pubmed.ncbi.nlm.nih.gov/31972853/},

year  = {2020},

date = {2020-02-01},

note = {University of Sydney et al},

keywords = {Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Neurological effects in the offspring after switching from tobacco cigarettes to e-cigarettes during pregnancy in a mouse model},

author = {Nguyen T, Li GE, Chen H, Cranfield CC, McGrath KC, GorrieCA.},

url = {https://pubmed.ncbi.nlm.nih.gov/31505003/},

year  = {2019},

date = {2019-08-29},

note = {University of Technology Sydney},

keywords = {Mice},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {A novel bone substitute with high bioactivity strength and porosity for repairing large and load-bearing bone defects},

author = {Jiao Jiao Li , Colin R Dunstan, Ali Entezari Qing Li , Roland Steck , Siamak Saifzadeh,, Ameneh Sadeghpour , John R Field Austin Akey, Martin Vielreicher, Oliver Friedrich, Seyed-Iman Roohani-Esfahani , Hala Zreiqat },

url = {https://pubmed.ncbi.nlm.nih.gov/30773833/},

year  = {2019},

date = {2019-08-04},

urldate = {2019-08-04},

note = {Queensland University of Technology, University of Sydney, Kolling Institute et al},

keywords = {Sheep},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Topographic organization of the ‘Third-Tier’ dorsomedial visual cortex in the macaque},

author = {Hadjidimitrakis K, Bakola S, Chaplin TA, Yu HH, Alanazi O, Chan JM, Worthy KH, Rosa MGP.},

url = {https://www.jneurosci.org/content/39/27/5311},

year  = {2019},

date = {2019-07-03},

note = {Monash University},

keywords = {Macaque, Non-human primates},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = { Intermittent fasting increasing energy expenditure and promotes adipose tissue browning in mice},

author = { Liu B, Page AJ, Hutchison AT, Wittert GA, Heilbronn LK.},

url = {https://www.sciencedirect.com/science/article/abs/pii/S0899900719300462?via%3Dihub},

year  = {2019},

date = {2019-06-01},

note = {University of Adelaide, South Australian Health and Medical Research Institute},

keywords = {Mice},

pubstate = {published},

tppubtype = {article}

}