@article{nokey,
title = {Chronic outcomes after mild-moderate traumatic brain injury in adult seizure-prone (FAST) and seizure-resistant (SLOW) rats: A model for understanding genetic contributions to acquired epileptogenesis?},
author = {Wai Lam Leung, Ali Shada, Piero Peruccaa, Terence J O’Brien, Bridgette D Semple, Pablo M Casillas-Espinosa},
url = {https://www.epilepsybehavior.com/article/S1525-5050(25)00086-1/fulltext},
doi = {https://doi.org/10.1016/j.yebeh.2025.110347},
year = {2025},
date = {2025-05-01},
urldate = {2025-05-01},
journal = {Epilepsy & Behavior},
volume = {166},
pages = {110347},
abstract = {This study looked at how genetics affect the risk of epilepsy after a brain injury. Researchers compared two types of rats: FAST rats, which are more prone to seizures, and SLOW rats, which are more resistant. After a mild brain injury, FAST rats had stronger early seizure-like responses, while SLOW rats showed more movement problems. Over time, both types of rats behaved differently, but the brain injury didn’t cause long-term epilepsy. Some abnormal brain activity was seen in FAST rats, but no full seizures. The study suggests that a different injury model may be needed to better understand the genetic risk for epilepsy.},
note = {Monash University},
keywords = {Epilepsy, Rats, TBI},
pubstate = {published},
tppubtype = {article}
}