@article{nokey,
title = {Safety and dosing of testosterone for hormone restoration in neutered dogs},
author = {Linda Brent, Florian Roeber, Eric Weber, Michael Chambers, Terry M Nett, Elaine A Lissner},
url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC12239267/},
doi = {10.1186/s12917-025-04869-8},
year = {2025},
date = {2025-07-09},
urldate = {2025-07-09},
journal = {BMC Veterinary Research},
volume = {21},
number = {449},
abstract = {This study looked at whether giving testosterone back to neutered male dogs is safe and what dose works best. Twelve neutered dogs were given weekly testosterone injections at different dose levels for 90 days. The researchers checked their blood hormone levels, general health, prostate size and behaviour throughout the study. They found that testosterone levels rose as expected and that even the highest doses did not cause major short-term health or behaviour problems. One hormone that is usually high after neutering (luteinizing hormone, or LH) decreased at higher testosterone doses, which may have potential health benefits. Overall, the treatment appeared to be well tolerated during the study period, though one dog with a past history of seizures had seizures again while on treatment. The findings suggest that carefully monitored testosterone therapy may be a possible option to restore hormones in neutered dogs. However, the study was small and short-term, and the researchers note that more research is needed to understand long-term safety.},
note = {Parsemus Foundation, Invetus Pty Ltd, Animal Reproduction & Biotechnology Laboratory},
keywords = {Dog, Hormone},
pubstate = {published},
tppubtype = {article}
}